Affective disturbance following traumatic brain injury: Severity of injury and the symptom-checklist-90-R

Symptom checklist-90 revised scores in persons with traumatic brain injury: affective reactions or neurobehavioral outcomes of the injury?

The goal of this study was to examine the concurrent validity of the Symptom Checklist-90 Revised (SCL-90-R) as a measure of emotional distress among persons with traumatic brain injuries (TBI). Following previous studies, the scale was divided into a "Brain Injury Subscale" (BIS), composed of items that are confounded with the neurobehavioral outcomes of TBI, and a "Non Brain Injury Subscale" ...

Affective Stimulus Processing following Traumatic Brain Injury

Symptom complaints following combat-related traumatic brain injury: relationship to traumatic brain injury severity and posttraumatic stress disorder.

Patients with a history of mild (n = 134) or moderate-to-severe (n = 91) TBI were asked to complete the Neurobehavioral Symptom Inventory (NSI) and the Posttraumatic Stress Disorder Checklist. Consistent with prior research, significantly more postconcussion symptoms were endorsed by the mild group. After controlling for age, time since injury, and mechanism of injury, TBI severity continued to...

Sleep disturbance and melatonin levels following traumatic brain injury.

OBJECTIVES Sleep disturbances commonly follow traumatic brain injury (TBI) and contribute to ongoing disability. However, there are no conclusive findings regarding specific changes to sleep quality and sleep architecture measured using polysomnography. Possible causes of the sleep disturbances include disruption of circadian regulation of sleep-wakefulness, psychological distress, and a neuron...

The Effects of Cyclooxygenase Inhibitors on the Brain Inflammatory Response Following Traumatic Brain Injury in Rats

Objective(s) Cytokines such as IL-1β are involved in inflammatory responses. This study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain IL-10 and IL-1β after traumatic brain injury (TBI) in male rats. Materials and Methods Rats were assigned into 6 groups: intact, sham, TBI, and treated rats with vehicle, celecoxib or iboprophen. Cytokine concentrations ...